Newcastle United are back in the Premier League under the management of Benitez, who led them to the Championship title last term, and he is looking forward to facing the Reds.
Benitez told the club official website that, "It's always exciting to see the new fixtures and like the fans, it's something we all look forward to."
"The two games with Liverpool will be extra special for me, but really every game is exciting and every game has it's own challenges."
The Spaniard added: "It's a great start at home to Tottenham and a really exciting first game at St James' Park for our fans to enjoy.
"We will all have extra motivation for that game, but it will be a very tough start too because Spurs showed how good they are last season.
"Of course they were our last Premier League opponents here too, which was a memorable match for everyone, but this time around it will be completely different."
Benitez famously won the Champions League with the Merseyside giants in 2005, during his six-year spell at Anfield.